Detection of SARS-CoV-2 contamination in the operating room and birthing room setting: a cross-sectional study
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SciScore for 10.1101/2021.09.03.21262874: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics IRB: This study was approved by both hospitals’ Research Ethics Boards
Consent: Environmental samples (air samples and floor samples) in the operating room or delivery suite were obtained with no patient or HCW consent required.Sex as a biological variable Study Samples (Appendix A included for detail): Patient sampling for any laparotomy cases included peritoneal cavity fluid (male or female). Randomization not detected. Blinding Aside from the cautery and active air sample filters, the lab staff were blinded to the source of the sample. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. …
SciScore for 10.1101/2021.09.03.21262874: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics IRB: This study was approved by both hospitals’ Research Ethics Boards
Consent: Environmental samples (air samples and floor samples) in the operating room or delivery suite were obtained with no patient or HCW consent required.Sex as a biological variable Study Samples (Appendix A included for detail): Patient sampling for any laparotomy cases included peritoneal cavity fluid (male or female). Randomization not detected. Blinding Aside from the cautery and active air sample filters, the lab staff were blinded to the source of the sample. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:It is possible that the true positive rates are higher since there are known limitations with the sampling and testing techniques used in this study6,34,35,40,42. We looked for characteristics of the patients’ infections that would increase the risks of detection of viral RNA in the surgical/obstetrical fields or local environment. Higher viral load detected on the initial NP swab (as estimated by the Ct threshold) was associated with a higher risk of detectable virus in our samples, while the subtype of the SARS-CoV-2 virus was not (although the numbers were insufficient for sub-analysis on viral subtyping). This study was not able to determine if the origin of aerosolized/droplet virus is arising from the surgical fields in the smoke plume. Others did not detect SARS-CoV-2 in electrocautery smoke despite using high viral loads in an in vitro setting28. While the lack of any positive viral RNA found on the smoke evacuator filters tested would indicate that the viral contamination from the surgical field is absent or below detection limits, these results cannot be used to definitely conclude that surgical smoke does not harbour SARS-CoV-2. Since infection with SARS-CoV-2 is primarily via the respiratory tract, we chose to sample the inside of HCWs masks as a means of identifying viral contamination in close proximity to the HCWs respiratory tract. Face mask sampling has previously been shown to be an efficacious way of detecting Mycobacterium tuberculosis contamination55 and ...
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a protocol registration statement.
Results from scite Reference Check: We found no unreliable references.
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