Clinical and Economic Effects of Widespread Rapid Testing to Decrease SARS-CoV-2 Transmission

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Abstract

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  1. SciScore for 10.1101/2021.02.06.21251270: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    In addition to the many limitation surrounding any model-based evaluation, our analysis does not account for the potential benefits of regular, inexpensive, rapid testing in other, more targeted settings. Schools, factories, air travel, concerts, recreational sports, large family celebrations, and places of worship might choose to make such testing a pre-requisite of participation. Since a small number of people with COVID-19 account for a high proportion of secondary cases, such a strategy would remove some of the most contagious individuals from crowded settings, eliminating case clusters and preventing super-spreader events.31 Some observers have questioned the ability of frequent, rapid, antigen testing to reduce transmission, raising several concerns.9 These include the lower sensitivity of antigen testing compared to PCR-testing (raising the risk that infectious people will remain in public on the erroneous belief that they are not infectious), the high number of false-positive tests leading to unnecessary isolation, poor adherence to the recommended testing and isolation recommendations, and the massive expense if testing is broadly applied. We acknowledge these concerns and, wherever possible, we have tried to give them voice by adopting modeling assumptions and input data values that tip the scales against nationwide antigen-based home testing. The strategy of frequent rapid testing to reduce SARS-CoV-2 transmission and decrease COVD-19 cases began generating widespr...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

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