Hiatal Hernia Size and De Novo Gastroesophageal Reflux Disease After Sleeve Gastrectomy: A Single-Center Retrospective Study
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Background
Sleeve gastrectomy is the most frequently performed bariatric procedure worldwide but is associated with the development of de novo gastroesophageal reflux disease (GERD). Hiatal hernia has been identified as a relevant anatomical factor in postoperative reflux, although most studies evaluate it dichotomously without analyzing whether its size influences GERD risk. The aim was to evaluate the association between preoperative hiatal hernia size and de novo GERD after sleeve gastrectomy.
Methods
Retrospective, single-center, observational study of patients undergoing sleeve gastrectomy at Hospital Central Norte de Petróleos Mexicanos (2018–2025). Demographic and clinical characteristics, endoscopic classification of hiatal hernia size (small <2 cm, medium 2.1–4 cm, large >4 cm), and evidence of de novo GERD were analyzed using descriptive statistics, Fisher’s exact test, odds ratio (OR) estimation with 95% confidence intervals (CI), and binary logistic regression. Statistical significance was set at p<0.05.
Results
Fifty-six patients were included (mean age 48.3 ± 8.1 years; 67.9% male). Hiatal hernia classification was conclusive in 46 patients (82.1%): 63.0% no hernia, 4.3% small, 30.4% medium, and 2.2% large. De novo GERD occurred in 14.0% of patients without preexisting GERD (6/43). No significant association was found between hiatal hernia size and de novo GERD (Fisher p=0.515). In the reduced logistic model, neither hiatal hernia (medium/large vs. absent/small; OR 3.47; 95% CI 0.50– 29.43; p=0.207) nor age (OR 1.02; 95% CI 0.90–1.13; p=0.754) was significantly associated. No evaluated factor (sex, smoking, alcohol, age) reached significance.
Conclusions
In this cohort, no statistically significant association was demonstrated between preoperative hiatal hernia size and de novo GERD after sleeve gastrectomy; however, the low number of events limits the ability to exclude a clinically relevant association. These findings are compatible with a multifactorial mechanism rather than with the isolated presence of this finding. Prospective studies with larger sample sizes and standardized reflux assessment instruments are required to confirm these results.
