Number of previous caesarean deliveries, history of vaginal birth and uterine rupture during a trial of labour : Protocol for a retrospective population-based cohort study

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Abstract

There remains considerable uncertainty around the safety of a trial of labour after more than one caesarean delivery. This large retrospective cohort study will investigate the safety of a trial of labour using a large United States dataset of all registered births from 2011 to the most recent year with available data. A multivariable fitted model will be used to predict the probability of uterine rupture in women with two or more previous caesarean deliveries, with a minimum 21-month interpregnancy interval. This will provide important information to clinicians in counselling women wanting to attempt a vaginal birth after more than one caesarean delivery.

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