golgi: open-source software for automated nerve model generation and recruitment simulation
Discuss this preprint
Start a discussion What are Sciety discussions?Listed in
This article is not in any list yet, why not save it to one of your lists.Abstract
golgi is an open-source platform that takes a peripheral nerve from image to stimulated fiber population through a single graphical interface, with an equivalent scriptable Python API and command-line interface for batch and high-performance use. It integrates promptable image segmentation, automated multi-region tetrahedral meshing, anisotropic finite-element solution of the extracellular field with an explicit perineurium contact impedance, generation of realistic fiber populations and their three-dimensional trajectories, and biophysical activation thresholds through interchangeable backends— NEURON (via PyFibers) and a GPU-accelerated surrogate (AxonML). Every study exports as an integrity-hashed bundle whose image-to-recruitment provenance is verifiable byte-for-byte. golgi lowers the barrier to in-silico peripheral nerve stimulation modeling for experimentalists and clinicians, using a fully open finite-element stack with no commercial dependencies.