LVentiView: An Open-Source Software for Automated 3D Left Ventricular Mesh Reconstruction and Analysis from Cardiac MRI

Patient-specific cardiac modeling requires accurate three-dimensional representations of the left ventricle (LV) reconstructed from cardiac magnetic resonance imaging (MRI). Here, we present LVentiView, an open-source software that bridges medical imaging and cardiac simulation by automating the full pipeline from MRI segmentation to simulation-ready volumetric meshes, with integrated tools for volumetric analysis and regional myocardial thickness calculation. We validate LVentiView on the Sunnybrook Cardiac Dataset, comprising healthy subjects and three cardiac pathologies. LVentiView achieves blood pool segmentation at the inter-expert level. The generated meshes are verified by comparing LV volumes extracted from the meshes to those computed from expert manual segmentation masks, with volumes and cardiac parameters agreeing within inter-expert variability across all four cardiac pathologies. In addition, mesh-derived regional thickness maps capture pathology-specific patterns, including wall thickening in hypertrophic cases. LVentiView is freely available on GitHub and provides an accessible, validated foundation for patient-specific cardiac modeling.