Single Cell Transcriptomic Re-analysis of Immune Cells in Bronchoalveolar Lavage Fluids Reveals the Correlation of B Cell Characteristics and Disease Severity of Patients with SARS-CoV-2 Infection
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SciScore for 10.1101/2020.11.09.374272: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Single-Cell RNA Sequencing: A publicly available data set was used for the analysis (Gene Expression Omnibus database, GSE145926). Gene Expression Omnibussuggested: (Gene Expression Omnibus (GEO, RRID:SCR_005012): Gene set enrichment analysis (GSEA) software (GSEA, version 4.0.3) was used for the analysis. Gene set enrichment analysissuggested: (Gene Set Enrichment Analysis, RRID:SCR_003199)The lists of DEGs were exported into a ranked file format and were uploaded to the GSEA … SciScore for 10.1101/2020.11.09.374272: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Software and Algorithms Sentences Resources Single-Cell RNA Sequencing: A publicly available data set was used for the analysis (Gene Expression Omnibus database, GSE145926). Gene Expression Omnibussuggested: (Gene Expression Omnibus (GEO, RRID:SCR_005012): Gene set enrichment analysis (GSEA) software (GSEA, version 4.0.3) was used for the analysis. Gene set enrichment analysissuggested: (Gene Set Enrichment Analysis, RRID:SCR_003199)The lists of DEGs were exported into a ranked file format and were uploaded to the GSEA software. GSEAsuggested: (SeqGSEA, RRID:SCR_005724)Results from OddPub: Thank you for sharing your data.
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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