From Neurons to Networks: A Holistic Review of Electroencephalography (EEG) from Neurophysiological Foundations to AI Techniques

Electroencephalography (EEG) has transitioned from a subjective observational method into a data-intensive analytical field that utilises sophisticated algorithms and mathematical models. This review provides a holistic foundation by detailing the neurophysiological basis, recording techniques, and applications of EEG before providing a rigorous examination of traditional and modern analytical pillars. Statistical and Time-Series Analysis, Spectral and Time-Frequency Analysis, Spatial Analysis and Source Modelling, Connectivity and Network Analysis, and Nonlinear and Chaotic Analysis are explored. Afterwards, while acknowledging the historical role of Machine Learning (ML) and Deep Learning (DL) architectures, such as Support Vector Machines (SVMs) and Convolutional Neural Networks (CNNs), this review shifts the primary focus toward current state-of-the-art Artificial Intelligence (AI) trends. We place emphasis on the emergence of Foundation Models, including Large Language Models (LLMs) and Large Vision Models (LVMs), adapted for high-dimensional neural sequences. Finally, we explore the integration of Generative AI for data augmentation and review Explainable AI (XAI) frameworks designed to bridge the gap between “black-box” decoding and clinical interpretability. We conclude that the next generation of EEG analysis will likely converge into Neuro-Symbolic architectures, synergising the massive generative power of foundation models with the rigorous, rule-based interpretability of classical signal theory.