Etiologic Subtypes of Ischemic Stroke in SARS-CoV-2 Patients in a Cohort of New York City Hospitals

  1. Ambooj Tiwari
  2. Ketevan Berekashvili
  3. Volodomyr Vulkanov
  4. Shashank Agarwal
  5. Amit Khaneja
  6. David Turkel-Parella
  7. Jeremy Liff
  8. Jeffrey Farkas
  9. Thambirajah Nandakumar
  10. Ting Zhou
  11. Jennnifer Frontera
  12. David E. Kahn
  13. Sun Kim
  14. Kelly A. Humbert
  15. Matthew D. Sanger
  16. Shadi Yaghi
  17. Aaron Lord
  18. Karthikeyan Arcot
  19. Adam A. Dmytriw

Reviewed by

Read the full article

Listed in

Log in to save this article

Abstract

No abstract available

Article activity feed

  1. Version published to 10.3389/fneur.2020.01004
  2. ScreenIT

    SciScore for 10.1101/2020.05.03.20077206: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementIRB: Retrospective case review protocol approval was obtained from the Institutional Review Boards at NYU School of Medicine, Brookdale Hospital University Medical Center, Jamaica Medical Center and Richmond University Medical Centers respectively.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    No key resources detected.

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Limitations: Our study has several limitations. This is a short analysis of neurovascular cases presenting to the hospital. As the number of cases in New York City and our hospitals continue to accumulate, we cannot determine the true rate of neurovascular events in COVID patients. Due to the stress on the resources created by COVID-19 some of the patients did not receive advanced imaging such as MRI to confirm whether a silent infarct may have occurred. Additionally, many cases had other risk factors and the embolic events may have been related to the underlying risk factor rather than the viral infection, or simply exacerbated by it. Finally, the type of strokes caused by the disease fit into several etiologic pathway rendering it difficult to delineate an appropriate treatment or prevention strategy.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2020.05.03.20077206v2 on medRxiv
  4. Version published to 10.1101/2020.05.03.20077206v1 on medRxiv