COVID-19 Clinical Characteristics, and Sex-Specific Risk of Mortality: Systematic Review and Meta-Analysis

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Abstract

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  1. SciScore for 10.1101/2020.03.24.20042903: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementIRB: The study did not require any ethics committee approval.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Search strategy: We searched Pubmed/Medline, Embase, Web of Science and the Cochrane Library for studies published from January 1, 2019 to March 3, 2020.
    Pubmed/Medline
    suggested: None
    Embase
    suggested: (EMBASE, RRID:SCR_001650)
    Cochrane Library
    suggested: (Cochrane Library, RRID:SCR_013000)
    Study Selection: The records found through database searching were merged and the duplicates were removed using EndNote X7 (Thomson Reuters, New York, NY, USA).
    EndNote
    suggested: (EndNote, RRID:SCR_014001)
    Data Synthesis and Analysis: Statistical analyses were performed with STATA (version 14,
    STATA
    suggested: (Stata, RRID:SCR_012763)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    This study has several limitations. Due to the rapidly emerging COVID-19 situation around the globe and the novelty of this coronavirus, there is still limited clinical data regarding diagnostic modalities and effective therapeutic measures. Most of the clinical findings were from observational studies. Future clinical trials and animal models are also required to have conclusive clinical information. We also need more studies outside of China for a comprehensive result that reflects COVID-19 globally. In the end, due to the lack of accurate reports of the new cases in different countries, the epidemiologic measures are also limited. As this pandemic is growing fast, future studies are needed for the evaluation of epidemiologic and clinical features of COVID-19.

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.