SARS-CoV-2 Codon Usage Bias Downregulates Host Expressed Genes With Similar Codon Usage

  1. Andres Mariano Alonso
  2. Luis Diambra

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  1. Version published to 10.3389/fcell.2020.00831
  2. ScreenIT

    SciScore for 10.1101/2020.05.05.079087: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    Antibodies
    SentencesResources
    On the other hand , a marked upregulation of inflammatory mediators at the protein level ( CXCL10 , CCL2 , IFN-α and γ ) has been observed in patients with SARS-CoV , without a significant amount of specific antibody ( 5) .
    CXCL10
    suggested: None
          <div style="margin-bottom:8px">
        <div><b>CCL2</b></div>
        <div>suggested: None</div>
      </div>
    
      <div style="margin-bottom:8px">
        <div><b>IFN-α</b></div>
        <div>suggested: None</div>
      </div>
    </td></tr></table>

    Results from OddPub: We did not find a statement about open data. We also did not find a statement about open code. Researchers are encouraged to share open data when possible (see Nature blog).

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore is not a substitute for expert review. SciScore checks for the presence and correctness of RRIDs (research resource identifiers) in the manuscript, and detects sentences that appear to be missing RRIDs. SciScore also checks to make sure that rigor criteria are addressed by authors. It does this by detecting sentences that discuss criteria such as blinding or power analysis. SciScore does not guarantee that the rigor criteria that it detects are appropriate for the particular study. Instead it assists authors, editors, and reviewers by drawing attention to sections of the manuscript that contain or should contain various rigor criteria and key resources. For details on the results shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2020.05.05.079087v1 on bioRxiv