Evaluation of Ozonized Fibrin-Rich Plasma as a Therapy for Facial Rejuvenation: A Clinical Case Study

AIM: To report the case of 5 patients who underwent facial skin treatment with ozonized fibrin-rich plasma (I-PRF). METHODS: This observational study of clinical instances involved 5 patients (4 women and 1 man), treated at the Unioeste dental clinic in Cascavel-PR. Treatment with ozonized I-PRF was performed in three sessions, focusing on areas such as the glabella, periorbital region, nasolabial fold, and chin. The protocol consisted of 5 consultations, including anamnesis, application of I-PRF, and final evaluations. RESULTS: The results showed a significant improvement in skin quality, reduction of expression lines, and decrease in hyperpigmentation, with individual variations. An improvement in facial muscle tone was also observed, demonstrating the overall rejuvenation effect. The treatment proved to be effective, providing a firmer texture and reducing skin imperfections. CONCLUSIONS: The data suggest that ozonated I-PRF can be used as a promising and innovative therapy for facial rejuvenation, with sustainable and satisfactory aesthetic results.