Effectiveness of Whole-Virus COVID-19 Vaccine among Healthcare Personnel, Lima, Peru
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Abstract
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SciScore for 10.1101/2022.03.16.22271100: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: Between November 25, 2020, and January 9, 2021, participants provided written informed consent and completed a baseline questionnaire about their demographics and role in the hospital (self-report exposure to COVID-19 patients (yes/no), work in intensive care unit (ICU) (yes/no), emergency department (ED) (yes/no)). Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the …SciScore for 10.1101/2022.03.16.22271100: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: Between November 25, 2020, and January 9, 2021, participants provided written informed consent and completed a baseline questionnaire about their demographics and role in the hospital (self-report exposure to COVID-19 patients (yes/no), work in intensive care unit (ICU) (yes/no), emergency department (ED) (yes/no)). Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:This study had at least four limitations. The high vaccine effectiveness we observed may be related to the short follow-up period after vaccination (range: 1-11 weeks after the two-week post-vaccination period; median of 2 weeks); a longer follow-up period is necessary to fully evaluate the long-term effectiveness of the vaccine among this study population. In addition, the study was not sufficiently powered to stratify VE estimates by variant or symptomatic vs asymptomatic infection. Moreover, because of the limited availability of laboratory staff and high volume of weekly respiratory specimens, we implemented a pooling strategy for SARS-CoV-2 testing which may have decreased sensitivity to detect those with low viral shedding. Last, our study could not distinguish nasal carriage of the virus from lower respiratory tract infection. In summary, one in ten healthcare personnel in our study in Peru tested positive for SARS-CoV-2 during February to May 2021. Vaccination of healthcare personnel with BBIBP-CorV vaccine was effective at reducing SARS-CoV-2 infections in the weeks immediately following vaccination. The data presented in this study supports the Peruvian Government’s ongoing COVID-19 vaccination efforts for reducing SARS-CoV-2 infections, especially among this critical workforce of healthcare professionals.
Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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