Exploring the mind-brain relationship to advance mental health research and practice

The mind-brain relationship (MBR) problem is an important philosophical pursuit with far-reaching implications for research and practice in the realm of mental health. Although there is a multitude of proposed resolutions to this quandary, the fundamental questions associated with MBR still persist unexplained. This article is an invitation to the reader to embark on an exploration of this issue by first delving into the nature of our subjective first-person experiences (that contributes to conceptualizing and defining the mind, as explained in the article), and then examining how third-person scientific understandings including understandings relating to the organ brain are arrived at. We explain that the first-person and third-person perspectives represent two distinct yet equally valid approaches to comprehend the world and our experiences within it, involving contrasting epistemological frameworks. We also describe that insights derived from the first-person perspective cultivate self-knowledge and wisdom, while those arising from third-person analysis illuminate the workings of the world. We additionally highlight that the mind constitutes a dynamic system—comprised of constantly changing sensory encounters and mental processes involving the present moment, the past, and the future—to be regarded as a distinct variable. Without denying the neurobiological correlates of mental states, this article serves as a catalyst for a broader, more inclusive approach to mental health research and treatment that can empower service providers, patients, as well as caregivers, and also help scientists to formulate more refined research inquiries pertaining to the mind and the brain.