Early Cognitive Screening for Individuals on the Alzheimer’s Disease Continuum
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Mild cognitive impairment is a critical transitional stage between normal aging and dementia, yet early detection remains challenging due to limitations in existing screening methods. Many traditional neuropsychological assessments are time-consuming, require specialized training, and are impractical for widespread use in primary care settings. In this study, we review the current landscape of cognitive screening tools and present a novel, fully automated screener based on two tasks from the Creyos cognitive assessment platform. This screener, designed for rapid administration without clinical supervision, effectively differentiates between cognitively normal individuals and those at risk of progression along the Alzheimer’s disease continuum. Validation analyses demonstrate that the screener has high sensitivity and specificity, outperforming many conventional assessments while promising to significantly reduce the burden on clinicians. By offering a brief, accessible, and reliable alternative to standard screening tools, this approach has the potential to enhance early detection efforts and facilitate timely intervention, ultimately improving patient outcomes and optimizing healthcare resources.