Early-Life Microbiota as a Key Modulator of Immune Development: Unveiling Novel Roles of Microbial Metabolites, Maternal Virome, and Probiotics
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The gut microbiota in early life plays a fundamental role in immune system maturation, metabolic regulation, and long-term disease susceptibility. While prior research has established the significance of maternal microbiota transfer, diet, and environmental factors in neonatal microbial colonization, emerging evidence suggests additional pathways influencing immune regulation. This study presents newly identified interactions between microbial metabolites, maternal virome activity, and precision probiotic interventions in modulating immune responses and reducing susceptibility to immune- mediated conditions.
