The Role of Dysregulated Ion Channels In Cancer Cells
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Bioelectricity refers to the electric current generated by cells through the movement of ions across the cell membrane. This review analyzes recent revelations regarding the relationship between bioelectricity and metastasis and explores the topic. The objective was to investigate how the dysregulation of ion channels may disrupt the bioelectricity network between cells, causing a change in membrane potential and resulting in metastasis. According to the literature, the high influx of calcium ions into the cell causes depolarization, resulting in abnormal cell behaviors frequently observed in cancer cells. Exploring the role of dysregulated ion channels in metastasis is important to understand how ion channels can be targeted clinically so that new treatment strategies for metastasis can be developed.
