Chronic Disease Management in Low-Resource Settings: A Case of Systemic Lupus Erythematosus and Acquired Haemolytic Anaemia

A woman in her mid-20s, who had been diagnosed with systemic lupus erythematosus (SLE), developed severe anaemia and haemolysis due to acquired autoimmune haemolytic anaemia (AIHA) and G6PD deficiency. She was living in a resource-limited setting, where managing her condition became increasingly difficult. Despite her previous diagnoses, her health deteriorated due to irregular treatment and loss to follow-up—mainly because of financial struggles and a lack of awareness about her disease.She was treated with blood transfusions, corticosteroids, and hydroxychloroquine, which helped resolve the haemolysis during follow-up. This case highlights critical global health challenges, such as the financial burden of chronic illnesses, the lack of proper patient education, and the systemic barriers that make consistent healthcare difficult in low-resource settings. It underscores the urgent need for more affordable treatment options, better patient education, and stronger healthcare systems to improve chronic disease management, especially for vulnerable populations.