Correlation between Proinflammatory Cytokines and Severity of COVID-19 within Palestinian Population

  1. Walid Basha
  2. Zaher Nazzal
  3. Yousef El-Hamshary
  4. Anwar Odeh
  5. Lama Hijjawi
  6. Mahmoud Doden
  7. Ahmad Musa
  8. Saad Ruzzeh

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Abstract

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  1. Version published to 10.26502/aimr.0106
  2. ScreenIT

    SciScore for 10.1101/2021.08.24.21262535: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsIRB: The Institutional Review Board (IRB) of An-Najah National University and the Ministry of Health Research Committee approved the study.
    Consent: Informed consent was obtained from each patient involved in this study, or from a member of the patient family.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Analysis and Ethical consideration: All statistical analyses were done with IBM SPSS Statistics for Windows, Version 20.0
    SPSS
    suggested: (SPSS, RRID:SCR_002865)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    This study has some limitations, including a limited sample size and a lack of time to follow up on patient changes. These factors may have played a role in the lack of a significant association of some of our findings, however they do not change the absence of any correlation between specific clinical severe symptoms and cytokine levels.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2021.08.24.21262535 on medRxiv