Accuracy of screening methods of COVID-19 in pregnancy: a cohort study

  1. Muhammad I. ALDIKA AKBAR
  2. Khanisyah E. GUMILAR
  3. Eccita RAHESTYNINGTYAS
  4. Manggala P. WARDHANA
  5. Pungky MULAWARDHANA
  6. Jimmy Y. ANAS
  7. Ernawati ERNAWATI
  8. Muhammad A. CAHYA LAKSANA
  9. Hermanto T. JOEWONO

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Abstract

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  1. Version published to 10.23736/s2724-606x.21.04979-4
  2. ScreenIT

    SciScore for 10.1101/2021.09.20.21263866: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsConsent: All participant were recruited for this study following informed consent.
    IRB: Ethical Consideration: This study has been approved by the Research Ethics Committee of Universitas Airlangga Hospital (Ref. No: 110/KEP/2021).
    Sex as a biological variableThis study is part of a cohort study of suspected COVID-19 cases in pregnant women in Universitas Airlangga Hospital (Surabaya, Indonesia) from April - August 2020.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Antibodies
    SentencesResources
    This test is used to detect the IgM and IgG antibodies to SARS-CoV 2 in human serum, plasma, or whole blood.
    IgG
    suggested: None

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    This study’s limitation is that the study population was all pregnant women with suspicion of COVID-19 infection. This matter will cause an unclear changes in clinical signs, laboratory, and additional examination because the control group was also a high-risk COVID-19 population. Furthermore, we cannot evaluate this screening method’s accuracy in the population of normal pregnant women (high and low risk) because of this inclusion criteria. We assume that the accuracy of this screening methods will be higher in the general population study. In a low middle income countries where the RT-PCR test was limited, the goverment can used the combined screening methods consist of clinical sign and symptoms, serological test, chest x-ray, and NLR to classify pregnant women with high risk of COVID-19 infection. Pregnant women with at least one sign from screening method can be further diagnose with RT-PCR test. This approach can be used in a limited resources hospital or health services in low middle income countries.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2021.09.20.21263866v1 on medRxiv