RETRACTED ARTICLE: Effectiveness of Ivermectin-Based Multidrug Therapy in Severely Hypoxic, Ambulatory COVID-19 Patients

  1. Sabine Hazan
  2. Sonya Dave
  3. Anoja W Gunaratne
  4. Sibasish Dolai
  5. Robert L Clancy
  6. Peter A McCullough
  7. Thomas J Borody

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Abstract

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  1. Version published to 10.2217/fmb-2022-0014
  2. ScreenIT

    SciScore for 10.1101/2021.07.06.21259924: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    EthicsConsent: Inclusion criteria were as follows 1) positive PCR for COVID-19; 2) informed consent; 3) age > 18 years, and 4) agreement to practice two highly effective methods of birth control if of childbearing potential.
    Sex as a biological variablenot detected.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Regression was carried out in Prism version 8 (GraphPad Prism software for Windows, San Diego, California USA, www.graphpad.com) using least square regression without weighting or special handling of outliers.
    Prism
    suggested: (PRISM, RRID:SCR_005375)
    All graphs were prepared by and statistical analysis done using GraphPad Prism version 8, and the error bar are indicative of the standard error of the mean (SEM).
    GraphPad Prism
    suggested: (GraphPad Prism, RRID:SCR_002798)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: We found the following clinical trial numbers in your paper:

    IdentifierStatusTitle
    NCT04482686RecruitingTrial of Combination Therapy to Treat COVID-19 Infection
    NCT04334512RecruitingA Study of Quintuple Therapy to Treat COVID-19 Infection
    NCT04949230RecruitingA Retrospective Study of COVID-19 Treatments

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2021.07.06.21259924v1 on medRxiv