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  1. SciScore for 10.1101/2020.05.15.20103119: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementIRB: Ethics: The study protocol was approved by Ethics Committee of the Italian National Institute of Health on 18th March 2020 and subsequently by local Institutional Review Board or Ethics Committee.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variableStatistical analysis: Univariate survival measures, with corresponding 95% confidence intervals (95% CI), at a fixed follow-up time (14 and 30 days) were computed with the Kaplan Meier estimator, for each covariate: age (<50, 50–59, 60–69, 70–79, 80–89, and ≥90 years), sex (males and females) and Charlson index (0, 1–2, and ≥3).

    Table 2: Resources

    No key resources detected.


    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).


    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    The availability of life-sustaining therapies or lack thereof should be considered when interpreting the COVID-19 mortality rate: poor outcomes may be due to known risk factors such as old age, frailty, comorbidities, profound disability, or because of effects of logistic limitations associated with lack of medical staff and medical staff burn-out, lack of beds and/or medical supplies. Moreover, although patients might indeed have SARS-CoV-2 infection, the infection itself may not necessarily be the cause of death. Extreme examples include patients with metastatic cancer or terminal organ failure.12 Due to the regional structure of the Italian NHS, the responses to the COVID-19 epidemic vary from region to region. The Lombardy region is home to a sixth of the Italian population (10·08 million inhabitants) and accounts for 37% of cases and 53% of deaths of the country, as of 21st April, 2020. The COVID-19 outbreak initially hit Italy in two small towns, Codogno and Vò Euganeo, in Lombardy and Veneto, respectively. The two outbreaks developed differently: in Lombardy the spread of infection was quick and several other clusters emerged rapidly;4 in Veneto, the first cluster had a limited spread until the diffusion of cases in all Northern Italian regions occurred. Finally, in Reggio Emilia the outbreak was related to the expansion of the first cluster occurring in the neighboring area of Codogno. Differences in the pattern of spread of the infection across the three areas are pr...

    Results from TrialIdentifier: No clinical trial numbers were referenced.


    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.


    Results from JetFighter: We did not find any issues relating to colormaps.


    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

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