Evaluation of the Effects of Shift Work on Cluster Headache Syndrome

Background: This study aimed to examine the impact of shift work on CHs and determine whether it affects headache chronicity. Methods: From 2014 to 2024, hospital database system files for patients diagnosed with cluster headache (ICD-10: G44.0) were retrospectively screened. Patients with at least 1 year of follow-up were evaluated for eligibility, and those who agreed to participate were either invited to outpatient clinic visits or contacted by phone. Results: Out of 113 patients who met the cluster headache diagnosis criteria, 78 agreed to participate in the study. Of these patients, 29.5% (n = 23) worked overnight shifts. Patients with cluster headache who work night shifts had significantly higher prevalence of chronic cluster and tobacco use than those who did not. Although not statistically significant, night shift workers were more likely to use alcohol and tobacco, as well as smoke more cigarettes per day. Conclusions: The shift schedule can significantly increase the frequency of bouts in cluster headache sufferers while also contributing to the disorder’s chronicity.