The risk factors associated with the postoperative hydrocephalus in traumatic brain injury patients undergoing decompressive craniectomy

Background and Objectives: Post-traumatic hydrocephalus (PTH) is a prominent complication that arises after decompressive craniectomy for traumatic brain injury ⁽¹⁾ , characterized by a multifaceted pathogenesis and substantial inter-individual variability. Accurate prediction of clinically significant risk factors necessitates the utilization of sophisticated statistical models. This study aims to identify potential risk factors to provide clinical support for the diagnosis and treatment of PTH. Methods : This study retrospectively analyzed the clinical data of 457 patients who underwent decompressive craniectomy for traumatic brain injury at the Department of Neurosurgery, Sir Run Run Shaw Hospital, between January 2015 and December 2022. Univariate analysis and binary logistic regression were conducted to identify risk factors. The resulting model was validated using three approaches: ROC curve analysis, decision curve analysis (DCA), and goodness-of-fit tests. Results : Based on the analysis of clinical data from these 457 patients, we identified several independent risk factors for PTH in patients with traumatic brain injury. Conclusion : By utilizing the outcomes of this article, we can identify and intervene at an early stage for effective treatment, ultimately enhancing the prognosis of individuals with TBI.