BiTreatment of Pediatric Lung Diseasesbliometric Analysis of the Application of Nanomaterials in the Treatment of Lung Diseases

Objective: To analyze the development trends in the field of nanomaterials for pediatric lung disease treatment from 2007 to 2024 based on bibliometrics. Methods: A total of 428 articles were extracted from the Web of Science database, and Citespace, VOSviewer, and R language were utilized for collaboration network analysis, keyword co-occurrence analysis, and burst analysis. Results: ① The annual publication volume has increased significantly since 2011, with the United States and China being the most productive countries, accounting for 65% of the total international collaborations; ② Research hotspots focus on nanomaterial-mediated immune modulation, targeted antibacterial therapy, and intelligent drug delivery systems; ③ Current breakthroughs are centered on optimizing the biocompatibility of materials and their applications in pediatric asthma and pneumonia, with future trends pointing towards nano-immune combination therapy, AI-assisted sensing, and remote monitoring technologies. Conclusions: The results indicate the need to establish an innovative system integrating nanomaterials, bioengineering, and intelligent monitoring, with a focus on enhancing the accuracy of targeted delivery, real-time efficacy assessment, and individualized treatment design to address the bottlenecks of delivery efficiency and long-term monitoring in traditional treatments. This study provides scientific guidance for optimizing nanomaterial-based therapeutic strategies for pediatric lung diseases and integrating interdisciplinary technologies.