Hydrogel droplets are generated and manipulated in a cylindrical cavity microfluidic environment- digital twin

This exploratory work focused on the hydrogel droplet generation and the numerical analysis for the digital twin. Hydrogel droplet technology has a wide range of applications in scientific research and engineering, and this paper reviews the hydrogel generation technology. The correlation analysis was carried out on the microfluidic droplet generation process under different experimental conditions, and the digital twin was discussed for the generation of microdroplets in the cylindrical cavity. The experiment mainly studied the size of the generated hydrogel microspheres by changing the concentration, flow velocity and pinhole diameter of the sodium alginate hydrogel solution. The experimental results show that the size of the droplets is positively correlated with the three experimental conditions, and is significantly correlated with the concentration of microfluidic solution and pinhole diameter. In this experiment, the role of three independent droplet generation factors is studied at the same time, which provides a digital twin technology basis for the realization of microfluidic hydrogel droplet generation.