Assessing the Gastroprotective Effects of Wild Marjoram Extract in Ethanol-Exposed Rat Models

Gastric ulcers, or injuries to the stomach wall layer, constitute crippled healing and are associated with the internal and external dangerous factors and the protective mechanisms of the body. This research aims to evaluate the effectiveness of a herbal preparation based on Wild Marjoram in preventing ulcers as compared to the conventional drugs omeprazole. The experiment included only male albino rats and contained several groups: positive control- treated with ethanol and dissected after one hour –was used, negative control-usual condition with no ethanol, groups pretreated with Wild Marjoram aqueous extract low dose (350mg/kg)-before ethanol and a high dose (650mg/kg) – before ethanol, and group treated with omeprazole twenty mg (20mg/kg). When using Wild Marjoram for high (83.42%) and low (78.51%) dosages, ulcer inhibition was shown. It was noted that omeprazole and control conditions denote rates of ulcer prevention with levels of eighty eight percent forty-seven only. Although the prevention of the index is higher when compared with that of omeprazole and cellular proliferation as well as, cell damage, wild marjoram prevented stomach complications with higher doses being more effective than lower doses.