The association between Serum Vitamian D Level with Attention Deficit Hyperactivity Disorder (ADHD) : A cross sectional comparative study in a sample of Egyptian Children

Background Attention-deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in childhood and adolescence. Dietary interventions such as omega-3 FA, vitamin and mineral supplementations might affect ADHD symptoms. Aim To compare serum level of vitamin D in children with ADHD with its different subtypes in relation to healthy controls. Methods A cross sectional comparative study was conducted on 108 children divided equally between healthy children and ADHD cases. Vit D was measured. Assessment of habitual vitamin D intake was done by using a vitamin D food frequency questionnaire. Results The median weekly vitamin D intake for the ADHD group was significantly lower than that for the control group, p < 0. 001. The ADHD group had significantly lower 25-Hydroxy Vitamin D level than the control group (p < 0. 001). Vitamin D level was considered independent predictor of ADHD susceptibility. Conclusion Patients with ADHD have lower serum concentrations of 25-hydroxyvitamin D than do healthy children.