Treatment Response to Antiretroviral Therapy in HIV Patients: A Cross-sectional Study at a Health Center, Vietnam in 2024

Background Human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) has remained a major global health concern since its initial discovery, exerting profound impacts on both the physical health and psychosocial well-being of affected individuals and their communities. Antiretroviral therapy (ART) is considered the cornerstone of HIV treatment, playing a critical role in improving patients’ quality of life and extending life expectancy. Objective To assess the characteristics, antiretroviral (ARV) usage rate, and treatment response among outpatients undergoing HIV treatment at District 3 Health Center in 2024. Methods A cross-sectional descriptive study was conducted using retrospective medical record data of HIV/AIDS patients receiving treatment at the Community Consultation and Support Department of the District 3 Health Center in 2024. Results Among the 318 HIV patients surveyed, 96.2% were receiving first-line ARV regimens, while 3.8% were on second-line regimens. The TDF + 3TC + DTG combination was the most commonly used regimen, accounting for 94.65% of cases. The findings showed that 98.69% of patients on first-line therapy and 91.69% of those on second-line therapy achieved treatment response. Conclusion The ARV treatment response rate was high, with the majority of patients receiving first-line regimens, among which the TDF + 3TC + DTG combination was the most predominant. Further analysis of treatment characteristics is necessary to assess their correlation with treatment response.