Myasthenia Gravis Complicated by Pulmonary Embolism and Deep Vein Thrombosis: A Case Report and Literature Review

Background To explore the potential association between myasthenia gravis (MG) and venous thromboembolism (VTE) and to raise clinicians’ awareness of MG as a potential risk factor for VTE. Case presentation We describe the diagnostic and therapeutic course of a patient with MG who developed deep vein thrombosis (DVT) and pulmonary embolism (PE) in the absence of traditional VTE risk factors (e.g., prolonged immobilization, malignancy), and we summarize the pertinent literature. The patient experienced DVT and PE during treatment for MG, without classic high-risk factors for VTE. Case details and literature synthesis together suggest a plausible mechanistic link between MG and thrombosis mediated by a chronic immune-inflammatory state. Conclusion MG itself may represent a potential independent risk factor for VTE, with immune-inflammatory activity sufficient to precipitate thrombosis. Clinicians should maintain a high index of suspicion for VTE in patients with active MG to facilitate early recognition, timely diagnosis, and intervention, thereby reducing the risk of severe outcomes such as fatal PE.