The application status of chlorhexidine in neonatal intensive care units in China

This study was dedicated to probing and dissecting the application circumstances of chlorhexidine gluconate (CHG) within neonatal intensive care units (NICU) across China. By means of self-designed questionnaires, the NICUs of 93 second-class grade A and above hospitals nationwide that partook in the survey were meticulously examined regarding the considerations, safety aspects, and challenges encountered during the utilization of CHG. The outcomes manifested that CHG was implemented in a comparatively limited number of NICUs. The users held the view that it exerted a favorable impact on the prevention and treatment of neonatal infections. Owing to its brief drying time, it was more amenable to acceptance by nurses. Nevertheless, there also existed some adverse reactions predominantly associated with skin conditions. The majority of hospitals that refrained from using it primarily took into account the restricted safety data for premature infants, apprehensions about off-label use, age elements, and cost considerations. There are individual disparities in the responses of diverse neonates to chlorhexidine gluconate. Currently, specific guidelines for the application of CHG in neonates are lacking, and prospective studies are requisite to appraise the optimal practices for the employment of CHG in neonates.