The effect of reducing the negative monetary externality of muscle injuries in professional football: evidence from the implementation of prevention methods.

Muscle injuries represent a major concern in professional football, generating significant financial losses due to player downtime, medical expenses, and reduced performance. Integrating physiogenomics, individualized training, and personalized nutrition offers a promising strategy to reduce injury incidence and improve team efficiency. This study evaluated the effectiveness of physiogenomic profiling combined with tailored nutritional programs in preventing muscle injuries and enhancing performance in professional football players, while estimating economic benefits for clubs. A predictive model based on previous studies estimated injury risk according to genotypes (RR, RX, XX). Personalized nutritional interventions were implemented during the 2024/25 season, with longitudinal monitoring of biochemical markers, injury incidence, and physical performance. Players with the XX genotype showed a notable decrease in injury frequency and severity, along with reductions in creatine kinase levels. Economic modelling estimated annual savings of €5 million per club in LaLiga and €11 million in the Premier League. JEL Codes: I12, I18, I15, L83, Q18, M54