Mortality in Adult Patients Admitted at Regional Hospital Bamenda Between 2015-2025 for Decompensated Liver Cirrhosis.

Background: Once decomposition has occurred, liver cirrhosis becomes a systemic disease. In turn, patients are burdened by a high risk of death. This worked aimed to study the mortality in adult patients admitted for decompensated liver cirrhosis at the Regional Hospital Bamenda. Specifically, to determine the mortality rate, identify the aetiologies of liver cirrhosis, and determine factors associated with mortality among our study participants. Methods : A cross-sectional analytical study was conducted involving 250 patients aged ≥18 years diagnosed with decompensated liver cirrhosis (DLC) at the Regional Hospital Bamenda. Data on Sociodemographic characteristics, clinical parameters, and outcomes were collected. Bivariate and multivariate logistic regression analyses were performed to identify factors independently associated with mortality. Results : Out of 46,301 patients admitted to the Regional Hospital Bamenda between 2015 and 2025, 250 adults with DLC were included in this study. The mean age was 48.31±14.91 years, with a male predominance (78.8%). The overall in-hospital mortality was 52.8%. Hepatitis B (68.0%), alcoholic liver disease (13.6%), and hepatitis C (11.2%) were the most common aetiologies of liver cirrhosis identified. Upon bivariate analysis, age >40 years, renal failure, hyponatremia, spontaneous bacterial peritonitis (SBP), and Child-Pugh class B/C were recruited for inclusion into the multivariate model. Multivariate logistic regression revealed that age >40 years [OR: 2.207; 95% CI, p=0.003], SBP (OR: 8.357, 95%CI, p=0.005), renal failure (OR: 2.190, 95% CI, p=0.044), hyponatremia (OR: 1.849, 95% CI, p=0.003), and Child-Pugh class B/C (OR: 1.862, 95% CI, p=0.030) were independent predictors of in-hospital mortality among patients with DLC. Conclusions : The in-hospital mortality of decompensated liver cirrhosis in the Regional Hospital Bamenda is very high. Chronic viral hepatitis and alcohol are the most encountered aetiologies of liver cirrhosis. Traditional factors: age >40 years, spontaneous bacterial peritonitis, renal failure, hyponatremia, and advanced Child-Pugh class (B/C) are independent predictors of in-hospital mortality.