The effect of hemoadsorption to postoperative outcomes of patients with Stanford Type A Aortic Dissection

Objective To investigate the effect of hemoadsorption on short-term outcomes of patients with Stanford Type A Aortic Dissection. Method The clinical data of 100 patients with TAAD from January 2021 to June 2023 were retrospectively analyzed. Patients were divided into HA group and CON group, depending on the usage of hemoadsorption during the cardiopulmonary bypass, with 50 patients in each group. The comparison between two groups including surgery-related indicators such as cardiopulmonary time, surgery time, clamping time, Deep Hypothermia Cardiac Arrest time, ultrafiltration volume, urine output as well as blood transfusion and clinical laboratory tests such as white cell count, aspartate aminotransferase, alanine transaminase, creatinine as well as blood urea nitrogen. All these tests were measured before surgery, at 24hrs and 48hrs after surgery. Results There was no significant difference for both baseline materials and surgery-related indicators between two groups (P>0.05). Compared with CON group, aspartate aminotransferase, alanine transaminase, creatinine and blood urea nitrogen in HA group improved, especially for alanine transaminase. Conclusion Hemoadsorption is valuable in improving and protecting liver and renal function within short-term period after TAAD surgery.