West Nile Virus lineage 2 neuroinvasive infection presenting as unilateral facial palsy

  1. Antonio Mastroianni
  2. Simone Malagò
  3. Valeria Vangeli
  4. Giuliana Guadagnino
  5. Luciana Chidichimo
  6. Maria Vittoria Mauro
  7. Francesca Greco
  8. Robert Tenuta
  9. Lavinia Berardelli
  10. Antonio Mori
  11. Sonia Greco
  12. Concetta Castilletti
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Abstract

We read with great interest the article by Wang A et al. (1) that discussed the mechanisms facial paralysis, caused by herpes simplex virus-1, herpes zoster virus, SARS-CoV-2, human immunodeficiency virus, and Epstein Barr virus. We retrospectively analyzed the clinical presentation of patients admitted to our hospital for West Nile virus encephalitis (WNE), from 2023 to 2025. We studied the phylogeny and molecular characteristics of some of the WNV strains, through sample preprocessing, sequencing, and bioinformatic analyses performed at Don Calabria Hospital in Negrar.

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  1. Version published to 10.21203/rs.3.rs-8338778/v1 on Research Square