Immune cell score model is a new tumor marker for predicting prognosis and selecting therapeutic drugs in thyroid cancer

Read the full article See related articles

Discuss this preprint

Start a discussion What are Sciety discussions?

Listed in

This article is not in any list yet, why not save it to one of your lists.
Log in to save this article

Abstract

Immune cells are widely distributed in the microenvironment of thyroid cancer, which promote or inhibit tumor development at different stages of tumorigenesis. The immune microenvironment of tumors may play an important role in tumor development. The number and function of immune cells infiltrated in different compartments of the tumor tissue affect the prognosis of tumor patients. The characteristics and clinical value of the immune microenvironment of thyroid cancer are unknown. In this study, the characteristic of the immune microenvironment of thyroid cancer was analyzed. The immune cell score was used to construct a risk model, and further investigated relationship between the model and the prognosis and drug sensitivity of thyroid cancer. The correlation between immune cells and immune genes was studied in the model. The model predicts the prognosis of thyroid cancer, identifies high-risk groups of thyroid cancer, and screens dominant populations benefiting from immunotherapy. It provides reference for prognosis evaluation and treatment strategy of thyroid cancer.

Article activity feed