Mapping the Global Research Landscape of HPV Vaccination and Oral Cancer

Oral cancer remains a significant global health challenge, with research focusing on the role of HPV vaccination in its prevention. This study aimed to fill that gap by analyzing publications related to HPV vaccination and oral cancer from 2012 to 2025, retrieved from the Web of Science Core Collection. Using tools like VOSviewer, CiteSpace, and the R package "bibliometrix," the analysis included 397 articles, revealing a steady increase in research output over time, with the United States leading in publication volume. Key institutions such as NCI, along with prominent authors like Giuliano AR, contributed significantly to the field. Emerging topics included vaccine innovations and economic evaluations. Despite growth, the research landscape remains geographically skewed, highlighting the need for expanded studies in underrepresented regions. This bibliometric analysis offers valuable insights into the development, collaborations, and future directions of HPV vaccination research related to oral cancer, guiding future efforts to achieve equitable global prevention.