Use of cyanoacrylate glue for mesh fixation and peritoneal flap closure in laparoscopic transabdominal preperitoneal repair of inguinal hernia

Laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair has gained popularity due to its association with less postoperative pain and shorter recovery period, compared to the open traditional techniques. This study evaluated the efficacy and safety of cyanoacrylate glue in TAPP repair, mainly focusing on its effect on postoperative pain. Cyanoacrylate glue was applied both for mesh fixation and peritoneal flap closure. A total of sixty patients with unilateral inguinal hernia were enrolled and followed-up for one year. The visual analog scale (VAS) was used to assess the pain during the early and late postoperative period. The mean operative time was 58 minutes and the mean time for peritoneal flap closure was 2.15 minutes. The VAS score at the first and seventh day was 2.77 and 1.5 respectively, while after one month the score was 0. There was no case of recurrence and no major complications were reported. The findings suggest that application of cyanoacrylate glue for mesh fixation and peritoneal flap closure is a safe and effective method with promising results. This technique seems to cause less postoperative pain compared to others described in the literature. However, large-scale randomized controlled trials should be carried out to confirm these findings.