Designing Functional Metal Complexes via a Schiff base From Disalicylaldehyde and Picolinohydrazide

Novel Schiff base ligand, N',N"-(1E,1'E)-(Methylenebis(6-hydroxy-3,1 phenylene))bis(methaneylylidene)di(picolinohydrazide), was successfully synthesized via a two-step procedure. The first step involved the acid-catalyzed condensation of salicylaldehyde with trioxane to form the precursor, 5,5'-methylenebis(2-hydroxybenzaldehyde). This dialdehyde was subsequently condensed with 2-picolinohydrazide in ethanol to yield the final bis-hydrazone Schiff base ligand. The structural identity of both the intermediate and the final ligand was confirmed using Fourier Transform Infrared (FT-IR) and Proton Nuclear Magnetic Resonance ¹ H-NMR) spectroscopy. The successful synthesis of this versatile ligand opens avenues for further exploration of its coordination chemistry and its potential applications in areas such as catalysis, chemical sensing, and biological activity.