Global assessment of the quality of care index for Burkitt Lymphoma from 1990 to 2021

Background Advances in medical technology have significantly improved the prognosis for Burkitt lymphoma (BL), but the quality of care remains a concerning issue. This study utilizes a modified Quality Care Index (QCI) to assess the global status of Burkitt lymphoma care. Methods Based on GBD 2021 data, we analyzed the burden of BL and its changing trends. Integrate the four secondary indicators through principal component analysis to construct QCI. Utilize the machine learning interpretability tool SHAP (SHapley Additive exPlanations) to deeply analyze the key factors affecting QCI. Employ the Bayesian age-period-cohort model to predict the QCI trends from 2022 to 2035. Results From 1990 to 2021, the age-standardized incidence rate (ASIR) of BL showed a significant upward trend (EAPC = 2.179), while the age-standardized mortality rate (ASDR) increased slowly (EAPC = 0.623). High Socio-demographic Index (SDI) regions had the highest incidence but lower mortality, whereas low SDI regions showed the opposite pattern. QCI was highly correlated with SDI, with a median QCI of 78.50% in high SDI regions and only 21.60% in low SDI regions. SHAP analysis indicates that age is the most important factor affecting QCI, followed by year and gender. Gender differences have reversed in recent years, with the quality of care for female patients gradually surpassing that for male patients. Predictions show that by 2035, the global QCI will stabilize at over 90%, and the advantage in the quality of care for female patients will be further consolidated. Conclusions The global burden of BL is increasing, with significant disparities in care quality, closely associated with age, time, gender, and geographic regions. To comprehensively improve the quality of global BL care, targeted interventions must be strengthened for regions with low SDI.