The relationship between lung function and obstructive sleep apnea: Finding from NHANES 2007-2008

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Abstract

Objective The purpose of this research is to explore the correlation between pulmonary function and OSA. Methods This research analyzed the data of 3824 participants from 2007 to 2008. Based on lung function, they are divided into obstructive group, trestrictive group, normal group, FEV1 < 80%pre group and FVC < 80% pred group. Logistic regression was used to analyze the relationship between lung function and high risk factors of OSA, and patients with COPD were screened by bronchodilation test to further analyze the high risk factors of COPD complicated with OSA. Results This research reveals that participants with OSA were older, had a greater proportion of males and smokers, exhibited larger waist circumferences and higher BMI. In addition, a significantly elevated risk of cardiovascular and cerebrovascular diseases. Univariate Logistic regression analysis showed that obstructive pulmonary ventilation dysfunction, FVC < 80%pred and cough with phlegm symptoms of the incidence rate was significantly higher in the OSA group. However, in the multivariate adjustment model, only chronic cough with phlegm were identified as independent risk factors for OSA. Further analysis of COPD complicated with OSA shows that gender, smoking, waist circumference and arthritis are independent risk factors。With the increase of the severity of airflow restriction, the incidence of COPD complicated with OSA is gradually increasing. Conclusion There is a certain correlation between lung function indexes and OSA. Regardless of factors adjusted for, chronic cough with phlegm remained a significant risk factor.

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