Correlation Between Oscillometry and Spirometry Parameters in Assessing Pulmonary Function in Pediatric Pulmonary Tuberculosis Survivor

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Abstract

Introduction : Despite successful treatment, pulmonary tuberculosis (TB) survivors often have lasting respiratory issues. Spirometry is the standard tool for assessing pulmonary function, but its utility is limited in pediatric populations due to cooperation challenges. Oscillometry offers a non-invasive alternative, yet its use in pediatric pulmonary TB survivor remains underexplored. This study evaluates the correlation between oscillometry and spirometry parameters in assessing pulmonary function among pediatric pulmonary TB survivors. Methods : A cross-sectional analytical study was conducted at Dr. Hasan Sadikin Hospital from January 2022 to April 2025. Pediatric pulmonary TB survivors aged between 5–<18 years underwent impulse oscillometry (PowerCube® ROS Box Ganshorn) to measure impedance (Z), resistance (R), reactance (X), resonance frequency (Fres), and reactance area (AX). Spirometry values included FEV1, FVC, and FEV1/FVC ratio. Pulmonary function patterns were categorized as normal, restrictive, obstructive, or mixed type. Pearson or Spearman correlation tests were used for analysis. Results : Forty-two subjects (66.7% female; mean age 15.93±4.15 years) completed oscillometry, and 34 of them underwent spirometry. The median duration following TB treatment was 17 months. Oscillometry identified restrictive patterns in 66.7% of subjects, whereas spirometry showed obstructive patterns in 35.3%, normal in 32.4%, restrictive in 20.6%, and mixed type in 11.8%. Significant negative correlations were found between R20 and FEV 1 (r = -0.413, p = 0.015), Z5 and FEV 1 (r = -0.458, p = 0.006), and Z5 and FVC (r = -0.419, p = 0.014). A positive correlation was observed between X5 and the FEV 1 /FVC ratio (r = 0.362, p = 0.035). Conclusion : In the population of pediatric pulmonary TB survivors, the results of oscillometry mostly showed pulmonary function with a restrictive pattern, while spirometry examinations provided an image of an obstructive pattern as the most frequent finding. Spirometry and several oscillometry parameters were significantly correlated in identifying respiratory limitation caused by prior pulmonary tuberculosis infection.

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