Transcriptomic Profiling of Muscle-Derived Stromal and Adipocytes Cells Exposed to Suborbital Microgravity
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Spaceflight negatively impacts skeletal muscle mass and function, and current countermeasures fail to completely offset those alterations. Innovative approaches are then needed to understand the mechanisms governing space-induced muscle changes. This study explores short-term microgravity (suborbital flight) effects on transcriptional profile of skeletal muscle mesenchymal cells and intramuscular adipose tissue. We identified a set of molecular factors and biological processes impacted by microgravity in these cell types, warranting further investigation.
