Metal-Free Carbenoid C–H Insertion: A Versatile Strategy for Constructing Fluorenes with Quaternary Carbon Centers

  1. Lili Wu
  2. Qiuzhan Huang
  3. Cong-Ying Zhou
  4. Chengming Wang
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Abstract

A metal- and light-free carbenoid C–H insertion procedure has been developed, enabling the rapid construction of various fluorenes with quaternary carbon centers. This methodology exhibits exceptional functional group tolerance, enabling the incorporation of a wide range of both activated and non-activated electrophiles.

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  1. Version published to 10.21203/rs.3.rs-7514325/v1 on Research Square