Normative Electrophysiological Values in the Pediatric Population: An ISCEV-Compliant Cross‑Sectional Study

  1. Mai A. Mohammed
  2. Amr M. Elhady
  3. Mohammed Hassan Khawaga
  4. Nancy Zakaria
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Abstract

Purpose: To set up age-stratified normative values for full‑field ERG (ffERG), multifocal ERG (mfERG), pattern ERG (PERG), and visual evoked potentials (VEP) in healthy children using ISCEV-standard protocols. Methods: Cross-sectional study on children aged 6 months–16 years. Ophthalmic examination and electrophysiological testing (ffERG, mfERG, PERG, VEP) performed per ISCEV standards. Responses analyzed for amplitude, latency, and age trends. Expected Results: Expect age-dependent increases in ERG/PERG amplitudes and reductions in VEP latencies, with maturation by adolescence. Significance: Provides comprehensive normative pediatric electrophysiology values to enhance diagnostic precision for retinal and optic nerve diseases.

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  1. Version published to 10.21203/rs.3.rs-7497112/v1 on Research Square