Mint Condition: Lamiaceae (Mentha) Species as Antidiabetic Agents

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Abstract

Diabetes mellitus is a complex metabolic disorder of insulin resistance and impaired insulin secretion, with various genetic and lifestyle causes. The limitations associated with conventional therapies, such as adverse affects and decreasing efficacy over time, warrant the need for exploration of better treatments. This gap is filled by plants with biologically active phytochemicals, readily available in natural environments and uncostly. Lamiaceae species, including those of the genus Mentha , have been studied in this context, demonstrating potential as antidiabetic agents. With the vast amount of scholarly information available, review articles are helpful for consolidation, synthesis, and convenience; a rapid review also accelerates this process, adapting the methods of a systematic review. Screened from 10,106 documents from databases ScienceDirect, PubMed, MDPI, ProQuest’s Global Health Library, and Sage Journals sourced in March 2025, this rapid review evaluates 15 modern research articles with evidence of the antidiabetic potential of Lamiaceae species through the guidelines from the Preferred Reporting Items for Systematic reviews and Meta-Analyses and the Cochrane Handbook for Systematic Reviews of Interventions. Further experimentation is warranted in Lamiaceae species especially to explore synergy with other plants, though existing data stimulates optimism for the future of diabetes treatment.

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