Scrub Typhus Induced Sepsis – A Rare Cause of Takotsubo Cardiomyopathy

Background: Takotsubo cardiomyopathy is a reversible left ventricular dysfunction, usually triggered by emotional or physical stress. Infectious causes are uncommon. We report a rare case of scrub typhus–induced Takotsubo cardiomyopathy, highlighting infection as a potential trigger. Case Presentation: A 62-year-old woman presented with fever, vomiting, and epigastric pain. She was hypotensive and tachycardic. Electrocardiography showed Q waves in V1–V3, and NT-proBNP was elevated. Serology confirmed scrub typhus. Echocardiography revealed reduced ejection fraction with apical hypokinesia. Cardiac MRI demonstrated apical ballooning and myocardial oedema without late gadolinium enhancement, consistent with Takotsubo cardiomyopathy and excluding infarction or myocarditis. She was treated with antibiotics, inotropes, and supportive therapy, with subsequent recovery. Conclusion: Scrub typhus can precipitate Takotsubo cardiomyopathy, a rare but reversible cause of acute cardiac dysfunction. Cardiac MRI is essential for diagnosis and exclusion of mimics. Early recognition and timely management improve outcomes.