Comparative Analysis of DVT Incidence After Posterior Lumbar Interbody Fusion(PLIF)and percutaneous endoscopic lumbar interbody fusion (PELIF): Identifying Risk Factors and Developing a Predictive Model
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Objective: This study aims to compare the incidence of deep vein thrombosis (DVT) between patients undergoing Posterior Lumbar Interbody Fusion(PLIF)and percutaneous endoscopic lumbar interbody fusion (PELIF) , identify independent risk factors, and develop a predictive model for postoperative DVT risk. Methods: This retrospective study included 207 patients who underwent PLIF and PELIF at our hospital from April 2024 to June 2025. Univariate and multivariate logistic regression analyses were conducted to identify independent risk factors for postoperative DVT. A predictive model was constructed based on these factors, and its discriminative ability was assessed using the area under the receiver operating characteristic (ROC) curve (AUC). Results: The incidence of DVT was significantly higher in the PELIF group compared to the PLIF group (P < 0.001). Univariate analysis revealed that age, intraoperative fluid administration, monocyte percentage, and D-dimer levels were significantly associated with postoperative DVT (P < 0.05). Multivariate logistic regression analysis further confirmed that age, intraoperative fluid administration, and monocyte percentage were independent risk factors. The predictive model constructed based on these factors had an AUC of 0.89 (95% CI: 0.82 - 0.95), indicating good discriminative ability. Conclusion: This study successfully identified independent risk factors for postoperative DVT in lumbar surgery patients and developed a predictive model with high discriminative ability. This model can serve as a practical tool for clinicians to assess postoperative DVT risk, optimize perioperative management, and reduce the incidence of DVT. Registry : Ethics Committee of Shanxi Bethune Hospital, Approval notice number: YXLL-2025-094, Registration date: 1st April 2025.