Comparative Study of Ransons Criteria and Modified Computed Tomography Severity Index (Mctsi) in Predicting Complication and Mortality in Acute Pancreatitis

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Abstract

Introduction : Acute pancreatitis (AP) is a sudden inflammation of the pancreas that can range from mild to severe. While mild cases resolve with supportive care, severe acute pancreatitis (SAP) is associated with high morbidity, complications such as systemic inflammatory response syndrome (SIRS), multiorgan failure, and mortality. Early diagnosis and severity assessment are critical in guiding treatment to improve patient outcomes. Ranson’s score and the Modified Computed Tomography Severity Index (CTSI) are commonly used to assess severity and predict complications in AP.Aim & ObjectiveThe aim of the study was to compare the effectiveness of Ranson’s score and the Modified CTSI in predicting mortality and complications in acute pancreatitis. The objectives included evaluating the efficiency of these scoring systems and examining the demographic profile of patients. Methodology : This observational study was conducted over 18 months at Santosh Hospital, with a sample size of 70 patients diagnosed with acute pancreatitis. Data were analyzed using SPSS software. Categorical variables were expressed as numbers and percentages, while quantitative data were presented as mean ± SD. Statistical comparisons were made using the student’s t-test and chi-square test, with a p-value of < 0.05 considered statistically significant. Results : The study revealed a male predominance (68.6%), with the highest age group being 31–45 years (35.7%). The mean Ranson’s score was 4.2 ± 1.1, and the mean Modified CTSI score was 6.8 ± 1.5. Complications were common, with necrosis (25.7%) and pseudocysts (21.4%) being most prevalent. Mortality was significantly associated with necrosis and multi-organ failure. Severe cases had higher readmission rates, with 8.6% of severe cases requiring readmission. Conclusion : The study found that both Ranson’s score and Modified CTSI are effective tools for assessing the severity of acute pancreatitis. The Modified CTSI score may provide a more detailed assessment. Severe cases showed higher rates of complications and readmissions, emphasizing the importance of early identification and targeted interventions in improving outcomes for high-risk patients.

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