Drug Multipication Theory
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The Drug Multiplication Theory (DMT) offers a fresh approach to understanding drug efficacy by modeling therapeutic outcomes through a biologically driven, multiplicative framework. At its core lies the Drug Multiplication Index (DMI), expressed as: DMI = (B × E × T) × R Here, B is bioavailability, E is effect strength, T is transformation coefficient, and R is receptor efficiency. This equation reframes how we predict drug effects—focusing less on how much drug is present in the bloodstream, and more on how the body amplifies or modifies that presence. Unlike traditional models built around linear dose-response curves or pharmacokinetic metrics like AUC and Cmax, the DMT framework highlights the biological “multiplier effect” that can make small doses surprisingly potent.
